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Swine Influenza Print E-mail
Life Sciences - Life Science Article
Written by Debjit Bhowmik   
Monday, 04 May 2009

swine-flu_by_gersh1.jpgRECENT ASPECTS OF SWINE INFLUENZA-AN OVERVIEW

Swine Influenza (swine flu) is a respiratory disease of pigs caused by type A influenza viruses that causes regular outbreaks in pigs. People do not normally get swine flu, but human infections can and do happen. Swine flu viruses have been reported to spread from person-to-person, but in the past, this transmission was limited and not sustained beyond three people. It is a contagious respiratory disease of pigs caused by type A influenza viruses.

The whole 16 pages article is available for download at Downloads section of Faramavita.Net

Pigs are hit by regular outbreaks. There are many different types of swine flu and the current cases involve the H1N1 strain of type A influenza virus. While people do not normally catch it, humans can contract the virus, usually if they have been in close contact with pigs. It is also possible for the constantly changing infection to spread from person to person, which has happened in the latest outbreak. Experts believe it spreads in the same way as seasonal flu - through coughing and sneezing. The symptoms of swine influenza in people are similar to the symptoms of regular human seasonal influenza infection and include fever, fatigue, lack of appetite, coughing and sore throat. Some people with swine flu have also reported vomiting and diarrhoea. Influenza viruses are commonly circulating in the human and animal environment, with different strains causing illness in humans, bird and pigs. Seasonal influenza is caused by viruses that are adapted to spread in humans. Humans have some natural immunity to the strains that are in common circulation, and this immunity can be boosted byimmunisation with a vaccine. According to the Health Protection Agency, an influenza pandemic is defined as a new or novel influenza virus that spreads easily between humans. When new influenza viruses are introduced into the environment, humans do not have any natural immunity to protect against them.
The World Health Organisation has warned the outbreak has "pandemic potential" and countries have been advised to step up surveillance and preparation in case the infection spreads rapidly. Flu viruses have the ability to change and mutate, making it difficult for drugs manufacturers to ensure effective vaccines are available. The new version of the H1N1 virus is a mix of different animal and human versions of the disease. Mixing can lead to the development of changed viruses to which humans have little immunity. However, testing has shown that the antiviral drugs oseltamavir (Tamiflu) and zanamivir (Relenza) appear to be effective against the human swine influenza H1N1 strain. If the flu spreads over a wide geographic area and affects a large proportion of the population it goes beyond an epidemic and becomes a pandemic. According to the Health Protection Agency, an influenza pandemic is defined as a new or novel influenza virus that spreads easily between humans. When new influenza viruses are introduced into the environment, humans do not have any natural immunity to protect against them. Therefore, there is a risk that new influenza viruses could develop into a pandemic if the virus passes easily from human-to-human. This includes covering their nose and mouth when coughing or sneezing, disposing of dirty tissues promptly and carefully, washing hands frequently with soap and water and cleaning surfaces which are regularly touchedTransmission of Swine Flu . Some people have reported diarrhea and vomiting associated with swine flu. Like seasonal flu, swine flu may cause a worsening of underlying chronic medical conditions. Spread of this swine influenza A (H1N1) virus is thought to be happening in the same way that seasonal flu spreads. Flu viruses are spread mainly from person to person through coughing or sneezing of people with influenza. Sometimes people may become infected by touching something with flu viruses on it and then touching their mouth or nose. Infected people may be able to infect others beginning 1 day before symptoms develop and up to 7 or more days after becoming sick. That means that you may be able to pass on the flu to someone else before you know you are sick, as well as while you are sick. There is no vaccine available right now to protect against swine flu. But there are everyday actions that can help prevent the spread of germs that cause respiratory illnesses like influenza.Like people, pigs can get influenza (flu), but swine flu viruses aren't the same as human flu viruses. Swine flu doesn't often infect people, and the rare human cases that have occurred in the past have mainly affected people who had direct contact with pigs. But the current swine flu outbreak is different. It's caused by a new swine flu virus that has spread from person to person -- and it's happening among people who haven't had any contact with pigs. The new swine flu virus apparently spreads just like regular flu. You could pick up germs directly from an infected person, or by touching an object they recently touched, and then touching your eyes, mouth, or nose, delivering their germs for your own infection. That's why you should make washing your hands a habit, even when you're not ill. Infected people can start spreading flu germs up to a day before symptoms start, and for up to seven days after getting sick, according to the CDC. The swine flu virus can become airborne if you cough or sneeze without covering your nose and mouth, sending germs into the air. The new swine flu virus is sensitive to the antiviral drugs Tamiflu and Relenza. The CDC recommends those drugs to prevent or treat swine flu; the drugs are most effective when taken within 48 hours of the start of flu symptoms. But not everyone needs those drugs; many of the first people in the U.S. with lab-confirmed swine flu recovered without treatment. The Department of Homeland Security has released 25% of its stockpile of Tamiflu and Relenza to states. Health officials have asked people not to hoard Tamiflu or Relenza. The symptoms of swine influenza virus are fever, confusion, disorientation, stiff joints, vomiting. One of the fatal symptoms of swine flu is the loss of consciousness as this may eventually lead to death. The swine flu virus mutates and evolves rapidly. New variant strains have evolved. The new strains were found to show resistance to standard antiviral drugs like amantadine and rimantadine for H3N2 in humans. In 2005, the resistance in humans was 91%.In 2005, the H5Ni virus was known to exits in pigs without showing symptoms. This finding was in Indonesia. The human transmission of swine flu is via contact with molecules that contain the virus. This means that human transmitted swine flu is spread through coughing, sneezing, touching, nose and mouth contact. The swine flu in a human is contagious during the first 5 days of the sickness. Some children and people can remain contagious for the first 10 days. In the US, swine flu is treated with amantadine, rimantadine, oseltamivir and zanamivir. However, some strains of swine flu virus have evolved to become resistant to the drugs. CDC recommends treatment with Tamiflu and RelenzaThe World Health Organization has not declared swine flu to be a pandemic. The WHO wants to learn more about the virus first and see how severe it is and how deeply it takes root. But it takes more than a new virus spreading among humans to make a pandemic. The virus has to be able to spread efficiently from one person to another, and transmission has to be sustained over time. In addition, the virus has to spread geographically. There are many different types of swine flu and the current cases involve the H1N1 strain of type A influenza virus. Influenza viruses are commonly circulating in the human and animal environment, with different strains causing illness in humans, bird and pigs. Seasonal influenza is caused by viruses that are adapted to spread in humans. Humans have some natural immunity to the strains that are in common circulation, and this immunity can be boosted by immunisation with a vaccine. Avian influenza is caused by influenza viruses adapted for infection in birds. Similarly, swine influenza is caused by influenza viruses adapted for infection in pigs. These illnesses all cause the same respiratory symptoms in sufferers and can be passed between one another. However, testing has shown that the antiviral drugs oseltamavir (Tamiflu) and zanamivir (Relenza) appear to be effective against the human swine influenza H1N1 strain, The World Health Organisation warned the outbreak had "pandemic potential" and countries were advised to step up surveillance and preparation in case the infection spreads rapidly. Flu viruses have the ability to change and mutate, making it difficult for drugs manufacturers to ensure effective vaccines are available. The new version of the H1N1 virus is a mix of different animal and human versions of the disease. Mixing can lead to the development of changed viruses to which humans have little immunity. If the flu spreads over a wide geographic area and affects a large proportion of the population it goes beyond an epidemic and becomes a pandemic.

The whole 16 pages article is available for download at Downloads section of Faramavita.Net

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