|Life Sciences - Life Science Article|
|Written by Rudjer Boskovic Institute|
|Saturday, 15 December 2007|
Protein fingerprinting made easy by Croatian scientists
Zagreb, 12.12.2007. - Combining some traditional experimental methods of molecular biology with computational methods of artificial intelligence, a group of researchers from Ruđer Bošković Instititute and Faculty of Natural Sciences and Mathematics from Zagreb, Croatia, demonstrated a novel approach for producing ‘protein fingerprints’ of diverse tissues. This result could lead to the development of new convenient methods in medical diagnostics.
Being directly responsible for a great majority of
processes in living cells, proteins are the most important class of
biological molecules. They are literally ‘molecular machines’ which
facilitate the import of nutrients into the cell and expulsion of waste
products from it, production of energy and transportation of material
within the cell, as well as cellular respiration and mechanical motion.
Due to their immense importance, proteins are among the most vigorously
studied topics in biology today. More...
Over half a million different
protein species have been identified in humans, each of them related to
particular types of human cells. Different tissues, such as muscles,
bones, nerves or skin, are distinguished by the unique ‘protein
fingerprint’ – the specific relative abundance of different proteins
contained in their cells. Moreover, pathological changes in any type of
tissue necessarily have an impact on the tissue’s protein composition,
and therefore protein fingerprinting can be used for early diagnostics
and identification of various diseases such as tumors or infections.
Source: PR - Ruđer Bošković InstitituteRead also at Pharmaceutical Licensing Network
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