Member Area

Farmavita.Net - Pharmaceutical Licensing Network

Thursday
Jul 31st
Eudragit Print E-mail
Life Sciences - Life Science Article
Written by Satish Singh Kadian   
Thursday, 22 October 2009

Eudragit and its Pharmaceutical Significance

One would always like to have an ideal drug delivery system that will possess three main properties: (a) It will be a single dose for the whole duration of treatment. (b) It will deliver the active drug directly at the site of action. (c) It will possess possible fewer side effects. Above approaches are achieved with the help of suitable choice of polymer.

The whole 17 pages article is available for download at Downloads section of Farmavita.Net.

This review focuses on recent literature regarding use of Eudragit polymer in different drug delivery systems with special attention to used in its fabrication along with their physiochemical properties.

A polymer, natural or synthetic is a substance that is combined with a drug or other active agent to release drug in a pre-designed manner. The development of NDDS has been made possible by the various compatible polymers to modify the release pattern of drug. Choice of polymers always suffering from the problems of non-biocompatible, non-biodegradable and expensive and this problem can solve with a polymer of different properties. The basic objective of controlled drug release is to achieve more effective therapies by eliminating the potential for both under- and overdosing. Other advantages are the maintenance of drug concentration within a desired range, fewer administrations, optimal drug use and increased patient compliance.

Eudragit is trademark of Rohm GmbH & Co. KG. Darmstadt in Germany, first marketed in 1950s. Eudragit prepared by the polymerization of acrylic and methacrylic acids or their esters, e.g., butyl ester or dimethylaminoethyl ester. Eudragit introduced in USPNF, BP, PhEur, Hand book of pharmaceutical excipients. The eudragit acrylic polymers have a long history of use, the individual types and grades being introduced in the following chronological order:

Year of introduction

 Eudragit Grade

1954

Eudragit L 12.5
Eudragit S 12.5

1959

Eudragit E 12.5

 

1961

Eudragit E 100 

 

1968

Eudragit RL 100
Eudragit RS 100

 

1972

Eudragit NE 30 D (formerly Eudragit E 30 D)
Eudragit L 30 D-55 (formerly Eudragit L 30 D)
Eudragit RS PO
Eudragit RL PO

1977

Eudragit L 100

 

1983

Eudragit NE 40 D

 

1985

Eudragit L 100-55 

 

1986

Eudragit RL 30 D
Eudragit RS 30 D
 

1999

Eudragit E PO
Eudragit FS 30 D
 

The whole 17 pages article is available for download at Downloads section of Farmavita.Net.

Comments
Search RSS
Only registered users can write comments!

3.26 Copyright (C) 2008 Compojoom.com / Copyright (C) 2007 Alain Georgette / Copyright (C) 2006 Frantisek Hliva. All rights reserved."

Read also at Pharmaceutical Licensing Network
Related News
Newer news items
Related Items
Farmavita.Net - The Pharmaceutical Licensing Network




Reddit!Del.icio.us!Google!Live!Facebook!Slashdot!Netscape!Technorati!StumbleUpon!Newsvine!Furl!Blogmarks!Yahoo!Ma.gnolia!FeedMeLinks!Free social bookmarking plugins and extensions for Joomla! websites!
 
< Prev   Next >
Advertisement
 

Featured Partners

 
150x150cancer.jpg
bals_150x150_anim.gif
latamm14_150x150_banner.gif   
150-150payers.jpg  
2014_pharmaci_banner_150x150.gif   
medaff14b_150x150.gif 
bals150_150x150.gif 
150x150copd.jpg 
2014-pmr-eur-banner-150x150.gif  

Login to Farmavita.Net

membership is FREE

Follow us on:




Join our LinkedIn Group

BabelFish Translator




Click Flag for Translation

Who's Online

We have 97 guests online

Farmavita.Net RSS News


Reports

rbdl0002_innovations-in-inj.gif 

Events

pc_150x150.gif

Reports

rbhc0264_privatehealthcare.gif 

REPORTS

farmavita_research-store.gif