|Life Sciences - Life Science Article|
|Written by Ravindra Patel|
|Tuesday, 21 July 2009|
PATHOPHYSIOLOGY, DRUG OFFERED AND CURRENT APPROACHES OF TRADITIONAL SYSTEM OF MEDICINE IN THE TREATMENT OF PEPTIC ULCER
Peptic ulcer generally occurs when there is an imbalance between aggressive gastric factors (acid, pepsin, Helicobacter pylori, refluxed bile salts) and defensive mucosal factors (gastric mucosal barrier, bicarbonate secretion, rapid cell turnover, high blood flow). The treatment of peptic ulcer is directed against reduction of aggressive factors or enhancement of mucosal defense of stomach and duodenum with cytoprotective agents.
The whole 19 pages article is available for download at Downloads section of Farmavita.Net
More recently, the role of mucosal factor in peptic ulceration has received much attention and the term "Cytoprotection" was first introduced by Andre Robert in 1979. In general it can be said that there is a plethora of mechanisms of gastric cytoprotection, their relative importance and interdependence being far from clarity. This itself is a point that gastric cytoprotection may be a multifactorial phenomenon. The present paper enumerates the various drug offered used in the treatment of peptic ulcer. Emphazises are made to co-relate the importance of various traditional system of medicine used.
Peptic ulcer disease refers to a group of disorders characterized by circumscribed lesions of the mucosa of the upper gastrointestinal tract (especially the stomach and duodenum). The lesions occur in regions exposed to gastric juices.
Peptic ulceration is an increasing cause of morbidity. Geographically, though the disease is prevalent throughout the world, incidence is more severe in U.K., U.S.A., and tropical countries like India. It is estimated that approximately 10-15% of world's population has peptic ulcer, with about 16 million cases reported in the United States. There are over 4 million hospitalization / year with about 1.5% of them ending in death.
The whole 19 pages article is available for download at Downloads section of Farmavita.NetRead also at Pharmaceutical Licensing Network
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