COMPARATIVE MARKET RESEARCH OF NORMAL TOOTH PASTE VS HERBAL TOOTH PASTE FROM UJJAIN CITY OF MADHYA PRADESH

The present paper through the light on the comparative marketing survey of normal and herbal tooth paste from the selected area of Ujjain city of Madhya Pradesh, India. Market research was carried in April 2011; data’s were collected from 5, general shop, 5 Doctors and 5 chemist of Ujjain city.  Results showed that the sale of normal tooth paste is higher than the herbal tooth paste due to several factors and some marketing strategies.

Full 4 pages Report is available for download at Downloads.

TOPRA Innovtion Award

Samarind, a leading provider of software to the regulatory affairs profession, announces its sponsorship of the 2011 TOPRA Innovation Award. The awards ceremony will be held at the Four Seasons Hotel in London's Docklands on 24th November.

As the inaugural winners of the award, Samarind has seen a significant benefit to its profile within the medicines and healthcare industry as a result, and is delighted to add its support to the innovation category for the coming year. Samarind's sponsorship will appear under the banner of its purpose developed regulatory management system, Samarind RMS.

Future Directions in Regenerative Medicine

This report covers the development of therapies to replace human cells or promote their regeneration: including cell therapies, tissue engineering, drugs, and medical devices. Each company profiled has at least one project in preclinical or Phase I study. Many also have later stage or launched products, which are covered briefly to illustrate the potential of the next generation of candidates.

Free Publication Features Wide Variety of Technology-Related Businesses, Organizations

(Research Triangle Park, N.C.) NCTechNews, a professionally edited online news publication dedicated to building a stronger technology community, is now accepting spring 2011 listings for its Innovation Resources Guide. No membership or fee is required to submit listings to and/or use the Guide, which is available at NCTechNews.com.
The Innovation Resources Guide provides links and detailed information for over 45 technology startups, established vendors, and nonprofits to help entrepreneurs and businesses gain needed access to products, services and information. 

“Technovation Entrepreneur 101” Shares Insight on Business Startup, Commercializing Scientific Discoveries

(Cary, N.C.) International strategic business consulting firm F.O.C.U.S. (TM) Resources, Inc. is hosting the educational webinar “Technovation Entrepreneur 101” on Wednesday, May 11 to help entrepreneurs gain insight into starting, growing, and running a successful business.

The webinar introduces START SMART (TM), GROW STRONG (TM), and RUN WELL (TM)  modules from the Technovation Entrepreneur (TM)  program for taking ideas, research, and innovations from concept to the marketplace. The webinar runs from Noon – 1 p.m. Eastern and is free; online registration is required at www.technovationentrepreneur.com. 

COMPARATIVE EVALUATION OF SOLUBILITY AND DISSOLUTION ENHANCEMENT OF BICALUTAMIDE SOLID BY DISPERSION TECHNIQUE

Bicalutamide is poorly water soluble Anti- Cancer drug used in prostate cancer. Due to poor solubility of drug, its bioavailability rate is limited by drug dissolution. In the present study, an attempt has been made to increase solubility and dissolution of Bicalutamide by solid dispersion technique using Solvent Evaporation and Hot Melt method with PEG- 6000 (Poly ethylene glycol), PVP K-90 (Poly vinyl pyrrolidone), and Poloxamer F-68.

The whole 6 pages article is available for download at Downloads section of Farmavita.Net 

CYCLOOXYGENASE-2 – AN ALLURING TARGET FOR MEANINGFUL DRUG DESIGNING

Cyclooxygenase, an enzyme involved in the conversion of C-20 acids to prostaglandins, exists in two isoforms. COX-1 is constitutively expressed and has a gastroprotective function. COX-2, induced at the site of injury, is responsible for the expression of pro-inflammatory prostaglandins. Despite overall similarities, COX-1 and COX-2 show subtle difference in amino acid composition at the active sites. COX-2 has valine at positions 89 and 523, while COX-1 has isoleucine, resulting in larger space availability in the former.

The whole 10 pages article is available for download at Downloads section of Farmavita.Net

ESTIMATION AND VALIDATION OF RESIDUAL SOLVENT BY GC HEAD SPACE MASS CHROMATOGRAPHY OF COLCHICINE USP

The present paper deals with the estimation and validation of residual solvent by GC head space mass chromatography of the drug Colchicine USP. The various parameters were evaluated and the data were presented in the present communications which establish the estimation and validation of the drug colchicines USP.

The whole 17 pages article is available for download at Downloads section of Farmavita.Net. 

Bayer Pharmaceuticals: Maintaining Market Share in the Pharma Industry

Interview with: Fabio Oris Piva, VP Global Strategic Marketing Men’s Health – Primary Care, Bayer Pharmaceuticals

“Gaining market share is always a challenge, even more so in the future… We should be ready for big changes,” says Fabio Oris Piva, VP Global Strategic Marketing Men’s Health – Primary Care, Bayer Schering Pharma. “We have to keep on inventing and initiating new activities to be competitive under these tough circumstances.” A speaker at the marcus evans PharmaBrand Summit 2011, in Montreux, Switzerland, 27 - 29 June, Oris Piva talks about marketing pharmaceuticals, boosting innovation and the role of social media in the industry. 

PREDICTION OF HUMAN INTESTINAL PERMEABILITY SINGLE-PASS INTESTINAL PERFUSION IN RAT: A QSAR/QSPR APPROACH

The aim of the study was the prediction of human intestinal permeability and fraction absorbed of oral dose using QSAR/QSPR methods. To explore physicochemical and topological properties of 15 compounds responsible for their Human intestinal permeability, a quantitative structure activity relationship, Hansch approach was applied on sixteen compounds. Various physicochemical and topological descriptors and reported Human intestinal permeability values of different 15 compounds were used as independent variables and dependent variable respectively.

The whole 5 pages article is available for download at Downloads section of Farmavita.Net. 

AD/PD 2011: Alzheimer’s companies showcase new data for marketed brands

Datamonitor recently attended the 10th International Conference on Alzheimer's and Parkinson's Diseases (AD/PD 2011) in Barcelona, Spain, held over March 9-13, 2011. Below are the highlights of the conference's coverage of currently marketed treatments for both diseases.

Forest, Lundbeck, and Johnson & Johnson were all present to promote their Alzheimer's disease drugs.

Pharmaceutical Key Trends 2011 – Biosimilar Market Overview

In 2009, the combined biosimilars market size for the US and five major European markets was $150m. With more than 30 branded biologics with sales of $51bn set to lose patent exclusivity between 2011 and 2015, Datamonitor forecasts that the global biosimilar market will grow from $243m in 2010 to $3.7bn in 2015.

Biosimilar market will reach $3.7bn in 2015

The global biosimilars market will grow from $243m in 2010 to $3.7bn in 2015 according to latest research from independent analyst, Datamonitor*.

More than 30 branded biologics with sales of $51bn set to lose patent exclusivity between 2011 and 2015*, and uptake of biosimilar versions will drive market growth.

Mark Hollis, healthcare analyst at Datamonitor, comments: “With the market shares of first-generation biologic drugs stagnating or declining, biosimilar monoclonal antibodies (MAbs) and second-generation biosimilars represent a high-value proposition for biosimilar manufacturers and key drivers for future growth”.

Enfield, UK March 22, 2011

Complete Plant Closure of Aesica Pharmaceuticals Enfield, UK Facility

As Phase 1 of a complete Aesica Pharmaceuticals facility closure, EquipNet is hosting a live and webcast auction of pharmaceutical API/chemical equipment in Enfield (North London) on 30 March, 2011. Beginning at 10:00 local time, the event will feature more than 1000 lots of high-quality, used and unused equipment. Featured items on the auction block include: tanks, reactors, mills, centrifuges, filters, glove boxes, deionized water systems, thermal oxidizers, pumps, heat exchangers, valves, critical spares, stockroom MRO, and lab equipment.

EVALUATION AND PHYTOCHEMICAL SCREENING OF SEED OIL OF NIGELLA SATIVA LINN.

Nigella sativa (Ranunculaceae) is a flowering plant, native to Southwest Asia. Seeds contain 36%–38% fixed oils, proteins, alkaloids, saponin and 0.4%–2.5% essential oil. The fixed oil is composed mainly of unsaturated fatty acids, including the unusual C20:2 arachidic and eicosadienoic acids. The seeds are used as a carminative and stimulant to ease bowel and indigestion problems and are given to treat intestinal worms and nerve defects to reduce flatulence, and induce sweating. The present paper deals with preliminary phytochemical screening of fixed oil obtained by the seeds. Also attempt was made to evaluate the oil so as to establish the standardization parameters.

The whole 4 pages article is available for download at Downloads section of Farmavita.Net.

Sheffield, UK Thursday 10th March 2011

Auction Sale of Forensic Science Equipment

Troostwijk Auctions have confirmed their instruction by the Forensic Science Service (FSS) to conduct an unprecedented online auction sale of forensic science equipment.  On Thursday 7th April 2011 the virtual hammer will fall on hundreds of nearly new analytical instruments and specialist forensic science equipment as part of the FSS’s ongoing transformation.

FOLKLORE USES OF AN ENDANGERED ETHNOMEDICINAL HERB OF INDIA SARCOSTEMMA ACIDUM. (SOMLATA)

Herbal medicines are in great demand in both developed and the developing countries in primary healthcare because of their great efficacy and little or no side effects. These traditional systems of medicine together with homoeopathy and folklore medicine continue to play a significant role largely in the health care system of the population. The tribals and rural population of India are highly dependent on medicinal plant therapy for meeting their health care needs. This attracted the attention of several botanist and plant scientists of several medicinal plants and there was a spurt of scientific literature. Somlata (Sarcostemma acidum) belonging to the family Asclepiadacea grown in India, Europe and US is an underutilized crop. 

The whole 7 pages article is available for download at Downloads section of Farmavita.Net.

Company Leasing New Office Space, Increasing Workforce

(Research Triangle Park, N.C.) ClinPharm Consulting, a specialized consulting firm offering a unique paradigm for empowering drug development pipelines, has moved into new offices in RTP and is hiring more employees to accommodate an expanding portfolio of clients and projects.

"We are experiencing high demand for our expertise in pharmacokinetics and overall clinical pharmacology drug development services,” said Chief Scientific Officer M. Alexander Shaw, Ph.D., adding, "Our complete knowledge of clinical pharmacology and high-quality scientific writing is paying dividends for our clients and their drug pipelines.”