Extended Release Multiunit Particulate System Download

Description:

A COMPREHENSIVE REVIEW ON SUSTAIN EXTENDED RELEASE MULTIUNIT PARTICULATE ORAL DRUG DELIVERY SYSTEMS

The term ‘Sustained Release' is known to have existed in the medical and pharmaceutical literature for many decades. Sustain release has been constantly used to retard the release of therapeutic agent such that its appearance in the circulation is delayed and/or prolonged and its plasma profile is sustained in duration. The onset of its pharmacological action is often delayed and duration of therapeutic action is sustained.
The object of sustain release of drug, in a general way is to modify the normal behaviour of drug molecule in a physiological environment. It can lead to the following.

• Sustaining drug action at a predetermined rate by maintaining a relatively constant, effective drug level in the body with minimization of desirable side effects.
• Localization of drug action by spatial placement of a controlled release system usually rate controlled adjacent to or in the diseased tissue of organ.
• Targeting drug action by using carriers of chemical derivatives to deliver drug to particular target cell type.
  

 

Submitted On:

27 Jul 2009

Submitted By:

Martina Ivanisevic (Martina)

File Date:

27 Jul 2009

File Author:

Debjit Bhowmik

File Size:

310.13 Kb

File Type:

pdf

Downloads:

214

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Total Votes:1

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