Drug resistance remains a major problem for the treatment of HIV. Resistance can occur due to mutations that were present
before treatment starts or due to mutations that occur during treatment. The relative importance of these two sources is
unknown. Resistance can also be transmitted between patients, but this process is not considered in the current study. We
study three different situations in which HIV drug resistance may evolve: starting triple-drug therapy, treatment with a
single dose of nevirapine and interruption of treatment.
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