The Antibacterial Activity of Benzimidazole Download

Description:

The Antibacterial Activity of Benzimidazole Derivative and the Quantitative Structure-Activity Relationships

QSAR study on benzimidazole derivatives using several topological and indicator descriptors was performed and evaluated for their antibacterial activities. The correlation equations of these relationships which were designed according to the Hansch Analysis Method were given. The 5 best models were selected for the discussion. Initial regression analysis indicated that balaban index plays a dominating role in modeling the activity in all proposed models. Results are interpreted on the basis of multiple regression and cross-validation methodology. Furthermore, the domain of applicability which indicates the area of reliable prediction is defined.

Submitted On:

11 Jun 2012

Submitted By:

Martina Ivanisevic (Martina)

File Date:

11 Jun 2012

File Author:

Prof. Vikas Pande

File Size:

233.60 Kb

File Type:

pdf

Downloads:

39

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Total Votes:0

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