QSAR study on benzimidazole derivatives using several topological and indicator descriptors was performed and evaluated for their antibacterial activities. The correlation equations of these relationships which were designed according to the Hansch Analysis Method were given. The 5 best models were selected for the discussion. Initial regression analysis indicated that balaban index plays a dominating role in modeling the activity in all proposed models. Results are interpreted on the basis of multiple regression and cross-validation methodology. Furthermore, the domain of applicability which indicates the area of reliable prediction is defined.
Monitoring news at Farmavita.Net
You can easily monitor all new articles published at Farmavita.Net . Click on the RSS button and bookmark the main RSS feed of Farmavita.Net. RSS button is located in URL field of your browser and also at the lower right side of every Farmavita.Net page